|
Symbol Name ID |
Cd19
CD19 antigen MGI:88319 |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased circulating IgA level |
Chronic decreased circulating total IgG |
Decreased circulating total IgM |
Reduced isohemagglutinin level |
Abnormal B cell count |
Decreased proportion of class-switched memory B cells |
Abnormal T cell count |
Recurrent sinusitis |
Conjunctivitis |
Recurrent otitis media |
Combined immunodeficiency |
Recurrent bacterial infections |
Recurrent respiratory infections |
| Disease(s) Associated with CD19 | |||||||||||||
| common variable immunodeficiency 3 |
| Mouse Phenotypes | decreased B cell proliferation |
abnormal B cell differentiation |
decreased neutrophil cell number |
decreased B-1 B cell number |
decreased B cell number |
increased CD8-positive, alpha-beta T cell number |
decreased lymphocyte cell number |
increased monocyte cell number |
absent spleen germinal center |
abnormal B cell physiology |
abnormal immunoglobulin level |
decreased IgA level |
decreased IgE level |
decreased IgG1 level |
decreased IgG2a level |
decreased IgG2b level |
decreased IgG3 level |
decreased IgM level |
decreased circulating interferon-gamma level |
decreased circulating interleukin-10 level |
decreased circulating interleukin-4 level |
decreased circulating interleukin-6 level |
decreased circulating tumor necrosis factor level |
abnormal humoral immune response |
increased interferon-gamma secretion |
decreased interleukin-10 secretion |
decreased tumor necrosis factor secretion |
increased susceptibility to experimental autoimmune encephalomyelitis |
decreased anti-nuclear antigen antibody level |
decreased anti-double stranded DNA antibody level |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
| Cd19em2(IMPC)Ics/Cd19em2(IMPC)Ics | |||||||||||||||||||||||||||||||
| Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn | |||||||||||||||||||||||||||||||
| Cd19tm1Tft/Cd19tm1Tft | |||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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